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Vasoconstrictor drug for topical use in ENT practice
Active substance
Release form, composition and packaging
◊ Dosed nasal spray (for children) 0.05%
◊ Nasal spray dosed 0.1% in the form of a clear, colorless solution.
Excipients: citric acid monohydrate, sodium citrate dihydrate, glycerol 85%, water for injection.
15 ml - dark glass bottles (1) with a dispensing device and a nosepiece - cardboard packs.
pharmachologic effect
Alpha adrenergic agonist for local use in ENT practice.
When applied topically, xylometazoline causes constriction of arterioles, leading to a decrease in hyperemia and swelling of the mucous membranes of the nasopharynx and a decrease in secretion. A distinct local effect of the drug is detected within a few minutes and persists for several hours (up to 6-8 hours), manifesting itself in the restoration of patency of the nasal passages, sinus openings and Eustachian tubes. Restoring air patency of the nasopharynx improves the patient’s well-being and reduces the danger possible complications caused by stagnation of mucous secretions.
Pharmacokinetics
When applied topically, xylometazoline is practically not absorbed, so the concentrations in the blood are very small (not analytically determined).
Indications
Rinonorm is used as symptomatic therapy for the following diseases and conditions:
- acute viral or bacterial rhinitis;
- acute allergic rhinitis;
- acute sinusitis or exacerbation of chronic sinusitis;
- spicy otitis media(to reduce swelling of the mucous membrane of the Eustachian tube);
— preparing the patient for diagnostic procedures in the nasal passages.
Contraindications
- atrophic (dry) rhinitis;
- angle-closure glaucoma;
— condition after hypophysectomy;
- simultaneous use of MAO inhibitors and tricyclic antidepressants;
— childhood up to 2 years (for spray for children);
- children under 10 years of age (for adult spray);
- hypersensitivity to xylometazoline or other components of the drug.
WITH caution the drug should be used for arterial hypertension, severe heart disease, hyperthyroidism, diabetes mellitus and patients taking.
Dosage
Adults and children over 10 years old Prescribe Rinonorm nasal spray 0.1%, 1 dose (1 press on the piston device) in each nasal passage no more than 3 times a day.
Children aged 2 to 10 years Prescribe Rinonorm nasal spray for children 0.05%, 1 dose (1 press on the piston device) in each nasal passage no more than 3 times a day.
The maximum possible use of the drug is no more than 7 times a day. The interval between drug administration should not be less than 6 hours.
The amount of liquid entering the patient’s nasal passage (1 dose) is 0.14 ml of solution.
To avoid complications in the form of resumption of symptoms of the disease, the duration of continuous use of the drug should not exceed 7 days.
Before using the drug, you should clear the nasal passages of secretions. During administration of the drug, you should take a light breath through the nose.
Side effects
Local reactions: burning sensation and dryness of the nasal mucosa; rarely - irritation of the mucous membrane of the nose, mouth and larynx.
Treatment: symptomatic therapy under supervision is indicated. In serious cases, non-selective alpha-blockers can be used to lower blood pressure, as well as intubation and mechanical ventilation. Vasoconstrictor drugs are contraindicated. In case of accidental ingestion of moderate or large quantity the drug orally, you should also take a laxative (for example, sodium sulfate), and do a gastric lavage.
Drug interactions
Concomitant use of tri- or tetracyclic antidepressants may increase the systemic exposure of xylometazoline.
When taking the drug simultaneously with MAO inhibitors, there may be a risk of increased blood pressure.
Rinonorm belongs to the class of vasoconstrictor drugs that have anti-inflammatory and antibacterial effects. It is used for diseases of the ENT organs, because its effect occurs within a few minutes and has a long-lasting effect (from 5 to 8 hours).
It reduces swelling of the mucous membrane and secreted secretions (improves the patency of the sinuses and nasal passages), which reduces the risk of complications of ENT diseases. Absorption of the active component (xylometazoline) of the drug in the blood plasma is insignificant.
Composition and release form
Rinonorm is packaged in a 10 or 15 ml bottle of tinted glass with a dosing nozzle and a transparent solution inside. Packed in cardboard boxes. The drug is produced in two types:
- Nasal spray for children (dosage of active substance 0.05%);
- Nasal spray for adults (0.1%).
Main component xylometazoline hydrochloride(1 and 5 mg). There are also excipients in the composition: glycerol (85%), sodium citrate dihydrate, citric acid monohydrate and water for injection.
Instructions for use
The drug is prescribed for the treatment of patients with various types(allergic, viral, bacterial), sinusitis and in complex therapy for the treatment of otitis media (with inflammation of the middle ear and infections of the auditory tubes). It can also be used during procedures in the nasal passages (to reduce swelling and pain of the procedure). The dose depends on sinus congestion.
Before starting the procedures, it is necessary to get rid of accumulated mucus and, when injecting (one press), inhale through the nose. The last injection is recommended before bedtime.
Dosage:
- Adults and children over 10 years of age (dosage 0.1% spray) - one injection (1 dose) alternately into the nasal passage.
- Children from two to ten (spray dosage 0.05%) also have one spray in each nasal passage.
Apply no more than 3 times a day and the interval should be 6 hours between the administration of the medicine. To avoid complications, it is not recommended to use the drug for more than a week. Repeated courses of using Rinonorm are possible with a break of three days.
Contraindications and side effects
Contraindications:
- Pregnancy and breastfeeding (no data available) clinical trials, can be used in exceptional cases and in pediatric dosage).
- Diabetes mellitus, severe heart disease, arterial hypertension (the drug can be used for such diseases only under the supervision of the attending physician).
- Do not use the spray under the age of 2 years.
- Sensitivity to the constituent components of the drug (xylometazoline, etc.).
- Kidney diseases.
- Atrophic rhinitis.
Side effects on the body in rare cases (usually in children) when taking the drug:
- Dryness, burning, itching, and sneezing often occur (but may go away on their own).
- Increased pressure.
- The occurrence of tachycardia.
- On the central nervous system - deterioration of health (headache, nausea, diarrhea).
- Allergic reactions and insomnia (extremely rare).
If these symptoms occur and an overdose of the drug occurs, you should stop using it and consult a doctor for further treatment under supervision.
Analogues
Since the main component of this product is xylometazoline, the analogues, respectively, are all containing drugs:
- Galazolin.
- Snoop.
- Xylene.
- Eucazoline.
Spray price
Rhinonorm price within from 50 to 80 rubles(depending on the release form and sales region).
Instructions for use
Rinonorm-teva 0.05% 15ml naz spray doser instructions for use
Dosage form
clear colorless solution
Compound
Xylometazoline hydrochloride 500 mcg
Excipients: citric acid monohydrate, sodium citrate dihydrate, glycerol 85%, water for injection.
Pharmacodynamics
Alpha adrenergic agonist for local use in ENT practice.
When applied topically, xylometazoline causes constriction of arterioles, leading to a decrease in hyperemia and swelling of the mucous membranes of the nasopharynx and a decrease in secretion. A distinct local effect of the drug is detected within a few minutes and persists for several hours (up to 6-8 hours), manifesting itself in the restoration of patency of the nasal passages, sinus openings and Eustachian tubes. Restoring air patency of the nasopharynx improves the patient’s well-being and reduces the risk of possible complications caused by stagnation of mucous secretions.
Pharmacokinetics
When applied topically, xylometazoline is practically not absorbed, so the concentrations in the blood plasma are very small (not analytically determined).
Side effects
Local reactions: burning sensation and dryness of the nasal mucosa; rarely - irritation of the mucous membrane of the nose, mouth and larynx.
From the side of the central nervous system: rarely - headache; rarely (< 1/10 000) - бессонница, повышенная возбудимость.
From the cardiovascular system: extremely rare (< 1/10 000) - аритмия, увеличение АД.
Other: rarely - nausea; rarely (< 1/10 000) - кожные реакции.
Selling Features
Available without a prescription
Special storage conditions
after opening the bottle - 1 year.
Special conditions
Impact on the ability to drive vehicles and operate machinery
There was no effect on the ability to drive vehicles or control machines and mechanisms.
Indications
Rinonorm is used as symptomatic therapy for the following diseases and conditions:
Acute viral or bacterial rhinitis;
Acute allergic rhinitis;
Acute sinusitis or exacerbation of chronic sinusitis;
Acute otitis media (to reduce swelling of the mucous membrane of the Eustachian tube);
Preparing the patient for diagnostic procedures in the nasal passages.
Contraindications
Atrophic (dry) rhinitis;
Angle-closure glaucoma;
Condition after hypophysectomy;
Simultaneous use of MAO inhibitors and tricyclic antidepressants;
Children under 2 years of age (for spray for children);
Hypersensitivity to xylometazoline or other components of the drug.
The drug should be used with caution in patients with arterial hypertension, severe heart disease, hyperthyroidism, diabetes mellitus and patients taking bromocriptine.
Use during pregnancy and breastfeeding
The drug should not be taken during pregnancy.
The drug should be used with caution during breastfeeding.
Drug interactions
Concomitant use of tri- or tetracyclic antidepressants may increase the systemic exposure of xylometazoline.
When taking the drug simultaneously with MAO inhibitors, there may be a risk of increased blood pressure.
Mode of application
Dosage
Children aged 2 to 10 years are prescribed Rinonorm nasal spray for children 0.05%, 1 dose (1 press on the piston device) in each nasal passage no more than 3 times a day.The maximum possible use of the drug is no more than 7 times a day. The interval between drug administration should not be less than 6 hours.
The amount of liquid entering the patient’s nasal passage (1 dose) is 0.14 ml of solution.
To avoid complications in the form of resumption of symptoms of the disease, the duration of continuous use of the drug should not exceed 7 days.
Before using the drug, you should clear the nasal passages of secretions. During administration of the drug, you should take a light breath through the nose.
Overdose
Symptoms: in rare cases of overdose, occurring mainly in children, arrhythmia, increased blood pressure, and in some cases loss of consciousness may be observed.Treatment: symptomatic therapy under supervision is indicated. In serious cases, non-selective alpha-blockers can be used to lower blood pressure, as well as intubation and mechanical ventilation. Vasoconstrictor drugs are contraindicated. If you accidentally ingest a moderate or large amount of the drug, you should take Activated carbon and a laxative (for example, sodium sulfate), perform gastric lavage.
Hello everyone!
Today I want to tell you about an inexpensive and effective spray for runny nose, which I buy for my daughter. We'll talk about Rhinonorm.
Until recently, we ourselves used the “adult” version of this medicine and were very pleased with it. You can read about it! By the way,I also used it for my daughter for a while, but then I finally decided to switch to the children's version. The dosage here is less, but the effect is no worse!
So!
The packaging of the spray is made in the recognizable style of the Teva brand: laconic and quite attractive. All the necessary information is present:
WITH reverse side you can see the composition of the spray:
Inside the package there is a bottle of medicine and instructions for use:
I'll start with the instructions
Like everyone else medicines, rhinonorm has
INDICATIONS FOR USE:
Acute viral or bacterial rhinitis;
Acute allergic rhinitis;
Acute sinusitis or exacerbation of chronic sinusitis;
Acute otitis media (to reduce swelling of the mucous membrane of the Eustachian tube);
Preparing the patient for diagnostic procedures in the nasal passages.
CONTRAINDICATIONS:
Atrophic (dry) rhinitis;
Angle-closure glaucoma;
Condition after hypophysectomy;
Simultaneous use of MAO inhibitors and tricyclic antidepressants;
Children under 2 years of age (for spray for children);
Children under 10 years of age (for adult spray);
Hypersensitivity to xylometazoline or other components of the drug.
METHOD OF APPLICATION AND DOSAGE:
Children aged 2 to 10 years are prescribed Rinonorm nasal spray for children 0.05%, 1 dose (1 press on the piston device) in each nasal passage no more than 3 times a day.
The maximum possible use of the drug is no more than 7 times a day. The interval between drug administration should not be less than 6 hours.
The amount of liquid entering the patient’s nasal passage (1 dose) is 0.14 ml of solution.
To avoid complications in the form of resumption of symptoms of the disease, the duration of continuous use of the drug should not exceed 7 days.
Before using the drug, you should clear the nasal passages of secretions. During administration of the drug, you should take a light breath through the nose.
The drug also has SIDE EFFECTS:
Local reactions: burning sensation and dryness of the nasal mucosa; rarely - irritation of the mucous membrane of the nose, mouth and larynx.
From the side of the central nervous system: rarely - headache; rarely (< 1/10 000) - бессонница, повышенная возбудимость.
From the cardiovascular system: extremely rare (< 1/10 000) - аритмия, увеличение АД.
Other: rarely - nausea; rarely (< 1/10 000) - кожные реакции.
And of course you need to know what to do when OVERDOSE:
Symptoms: in rare cases of overdose, occurring mainly in children, arrhythmia, increased blood pressure, and in some cases loss of consciousness may be observed.
Treatment: symptomatic therapy under supervision is indicated. In serious cases, non-selective alpha-blockers can be used to lower blood pressure, as well as intubation and mechanical ventilation. Vasoconstrictor drugs are contraindicated. If you accidentally ingest a moderate or large amount of the drug, you should take activated charcoal and a laxative (for example, sodium sulfate), and do a gastric lavage.
The bottle of the children's Rinonorm is no different from the adult version except the color of the cap: dark glass, an elongated spout, hangers, which make it convenient to use the bottle:
The tip of the bottle fits easily into the child’s nose and the spray is perfectly sprayed throughout his insides.
We switched to this spray at the end of last year. What can I say about him?
Despite the fact that the dosage of xylometazoline here is two times lower, the drug is not less effective. Plus, the aftertaste after it is softer and goes away much faster.
I know that many people do not like such vasoconstrictor drugs because they are addictive, resulting in dry mouth, etc. To prevent all of the above, I alternate between Rinonorm and Pinosol, because... the last one is oil. It not only treats a runny nose, but also moisturizes the mucous membrane.
Now about the effectiveness of our children's Rhinonorm. With a severe runny nose/nasal congestion, positive dynamics are observed already on the second day: there are noticeably fewer sniffles, and their consistency changes. And complete recovery occurs in about 5-6 days. It seems to me that this is a very good result!
I also began to drink this particular Rinonorm for myself. And you know, he helps no worse than an adult!
To sum up everything written above, I want to say that children’s Rinonorm is not expensive, but at the same time an effective drug that is suitable for both children and their parents!
BUT REMEMBER THAT THIS SPRAY IS A MEDICINE, SO YOU SHOULD CONSULT A DOCTOR BEFORE USING IT! ESPECIALLY THE PEDIATRIC!!!
Thanks for stopping by!!!