Rinonorm dosed nasal spray for children. Rhinonorm nasal drops for children and adults - indications, dosage, side effects, analogues and price. Release form, composition and packaging
Tradename
Rhinonorm
International Nonproprietary Name (INN)
Xylometazoline
Dosage form Rinonorm
dosed nasal spray
Composition of Rinonorm spray
10 ml spray contains:
Active substance:
Xylometazoline hydrochloride 10.0 mg
Excipients:
Citric acid monohydrate, sodium citrate dihydrate, glycerol 85%, water for injection.
Description of Rinonorm spray
Transparent colorless solution.
Pharmacological group
anticongestive agent - alpha-adrenergic agonist.
ATX Code
pharmachologic effect
Xylometazoline is an alpha-adrenergic agonist used for topical use in ENT practice.
When applied topically, Xylometazoline causes constriction of arterioles, which leads to a decrease in hyperemia and swelling of the mucous membranes of the nasopharynx and a decrease in secretion. A distinct local effect of the drug is detected within a few minutes and persists for several hours (up to 6-8 hours), manifesting itself in the restoration of patency of the nasal passages, sinus openings and eustachian tubes. Restoring air patency of the nasopharynx improves the well-being of patients and reduces the danger possible complications caused by stagnation of mucous secretions.
Pharmacokinetics
When applied topically, Xylometazoline is practically not absorbed, so the concentrations in the blood plasma are very small (not analytically determined).
Indications for use Rinonorm spray
As a symptomatic treatment for the following diseases and conditions:
- acute viral or bacterial rhinitis;
- acute allergic rhinitis;
- acute sinusitis or exacerbation of chronic sinusitis;
- spicy otitis media(to reduce swelling of the mucous membrane of the Eustachian tube);
- preparing patients for diagnostic procedures in the nasal passages.
Contraindications
- hypersensitivity to xylometazoline or other components of the drug;
- inflammation of the skin, nasal mucosa and crust formation (dry rhinitis);
- use after hypophysectomy;
- use in children under 10 years of age;
- angle-closure glaucoma;
- taking monoamine oxidase inhibitors (MAO) and tricyclic antidepressants.
Carefully
Use with caution in patients with arterial hypertension, severe heart disease, hyperthyroidism, diabetes mellitus and taking bromocriptine.
Use during pregnancy and lactation
The drug should not be taken during pregnancy. Use with caution during breastfeeding.
Method of application and dosage of Rinonorm spray
Adults and children over 10 years old:
1 dose (one press on the piston device) in each nasal passage no more than 3 times a day (the maximum dose should not exceed 7 times a day). The interval between drug administration should not be less than 6 hours.
1 dose = 0.14 ml of solution.
To avoid complications in the form of resumption of symptoms of the disease, the duration of continuous use of the drug should not exceed 7 days.
For use in children from 2 to 10 years of age, use Rinonorm, dosed nasal spray [for children].
Side effect
Sensation of burning and dryness of the nasal mucosa;
in rare cases - irritation of the mucous membrane of the nose, mouth and larynx, headache and nausea; rarely (< 1/10000) - аритмия, увеличение blood pressure, increased excitability, skin reactions.
Overdose
In rare cases of overdose, which occurs mainly in children, the following symptoms may be observed: irregular pulse, increased blood pressure, and in some cases, loss of consciousness. In case of overdose, symptomatic treatment under supervision is indicated.
In serious cases, non-selective alpha-blockers may be used to lower blood pressure, as well as intubation and mechanical ventilation. Vasoconstrictor drugs are contraindicated. In case of accidental ingestion of moderate or large quantity the drug should be taken orally Activated carbon(adsorbent) and sodium sulfate (laxative), perform gastric lavage.
Interaction with other drugs
Concomitant use of tri- or tetracyclic antidepressants may increase the systemic exposure of xylometazoline. When taking the drug simultaneously with monoamine oxidase inhibitors (MAOIs), there may be a risk of increased blood pressure.
special instructions
There was no effect on the ability to drive vehicles or control machines and mechanisms.
Release form Rinonorm spray
Nasal spray dosed 0.1%.
10 ml or 15 ml in a dark glass bottle with a dispensing device for spraying, a nasal nozzle and a protective cap.
1 bottle along with instructions for use in a cardboard box.
Availability and price in pharmacies Rinonorm spray
Storage conditions
Store at a temperature not exceeding 25°C.
Keep out of the reach of children!
Best before date
3 years, after opening the bottle - 1 year.
Do not use after the expiration date!
Conditions for dispensing from pharmacies
Available without a prescription.
Manufacturer
Merkle GmbH, Ludwig-Merkle Strasse 3, D-89143, Blaubeuren, Germany.
An organization authorized to accept complaints from consumers.
Rinonorm is a vasoconstrictor used in otolaryngology. The medication is available in the form of a nasal spray. The drug can be used in children over 2 years of age. Rinonorm can be used with caution by mothers who support breastfeeding.
Dosage form
The medication is available in the form of a nasal spray dosed at 0.05% and 0.1%.
Description and composition
Dosed nasal spray is a clear, colorless solution.
The drug contains as an active ingredient. In addition to it, the medication contains the following auxiliary components:
- glycerol;
- water for injections;
- E330;
- sodium citrate dihydrate.
Pharmacological group
Rinonorm is an α-adrenergic agonist for local use in ENT practice. narrows the arterioles, reduces hyperemia and swelling of the mucous membranes of the nasopharynx and the amount of secretion. The drug begins to act within a few minutes and the effect lasts up to 6-8 hours. After its spraying, the patency of the nasal passages and Eustachian tubes is restored.
When applied topically active substance practically not absorbed, therefore the concentration in the blood plasma is low and cannot be determined analytically.
Indications for use
for adults
The drug is used for the following diseases:
- acute rhinitis of viral, bacterial, allergic etiology;
- acute sinusitis or chronic in the acute stage;
- acute inflammation of the middle ear (spray is used to reduce swelling of the mucous membrane of the Eustachian tube).
In addition, Rinonorm is prescribed to prepare the nasal passages for diagnostic procedures.
for children
A spray in a dosage of 0.05% can be used according to indications in children over 2 years of age, a medicine in a dose of 0.1% is allowed for patients over 10 years of age.
for pregnant women and during lactation
Rinonorm is contraindicated during pregnancy. The spray can be used with caution by breastfeeding patients.
Contraindications
Rinonorm should not be used if the patient has:
- individual intolerance to the composition of the spray;
- atrophic rhinitis;
- condition after surgical destruction or removal of the pituitary gland;
- angle-closure glaucoma.
Rinonorm is contraindicated in patients undergoing treatment with MAO inhibitors and tricyclics.
Carefully medicine should be prescribed if the patient has:
- arterial hypertension;
- severe heart pathologies;
- thyrotoxicosis;
special instructions
Rinonorm does not affect the ability to drive a car.
Overdose
- arrhythmia;
- increased blood pressure;
- loss of consciousness.
Most often, symptoms of overdose are observed in children.
There is no specific antidote. The victim is prescribed symptomatic therapy. In case of severe intoxication, non-selective α-blockers are prescribed to reduce blood pressure, and intubation and mechanical ventilation are also performed. If the drug is mistakenly taken orally, laxatives such as sodium sulfate are prescribed, given to drink and gastric lavage performed.
Storage conditions
Rinonorm should be stored out of the reach of children at temperatures up to 25⁰C. The shelf life of the spray is 36 months; after opening the bottle, the medicine can be used for 12 months.
Analogues
You can buy Rinonorm without a prescription. In addition to it, many of its analogues are sold in pharmacies:
- Xylo is a complete analogue of the drug Rinonorm. Available in the form of a nasal spray at 0.05% (allowed for children 2-6 years old) and 0.1% (can be used in patients over 6 years old). Xylo should not be taken by pregnant or lactating patients.
- - a Polish drug that is a complete analogue of Rinonorm. The drug is available in the form of a nasal gel and spray. In a suitable dosage form, the drug can be used in patients over 2 years of age. prohibited for pregnant and lactating women.
- belongs to Rinonorm substitutes in the therapeutic group. The medicine is available in the form of drops and spray. The drug comes in several dosages, which allows it to be used in patients of different ages, including children in the first year of life. Can be used by pregnant women and breastfeeding women.
- Naphthyzin-plus is a substitute for the drug Rinonorm in the therapeutic group. The medication is produced in the form of nasal drops, which can be used for rhinitis in children over 12 months, pregnant women and those supporting breastfeeding during lactation.
- - a drug from the Zentiva company, which is a substitute for Rinonorm in the clinical and pharmacological group. The medicine is available in the form of a spray, drops and nasal ointment. The drug can be used in patients over 2 years of age, including pregnant women and breastfeeding women. The drug is contraindicated in allergic rhinitis.
Only the attending physician should select an analogue of the drug Rinonorm, since each of the medications has its own characteristics.
Price
The cost of Rinonorm is on average 70 rubles. Prices range from 56 to 173 rubles.
The cold season is traditionally considered the season of colds, viral infections, and flu. And closer to spring, many people begin to experience allergies, including a runny nose caused by this disease. Children catch colds and illnesses especially easily, so it is important for parents to know which drug can be taken so that their children recover quickly.
Release form
A well-known cure for the common cold is “Rinonorm”, which is available in the form of nasal remedies: drops, spray and gel. Moreover Manufacturers offer a special children's dosage with a reduced concentration of the active component. Parents can only choose more convenient form(drops or spray “Rinonorm” 0.05%).
The drops are sold in dark glass bottles with a pipette cap of 10 and 15 ml and in spray bottles of 10 and 15 ml with a convenient spray cap that dispenses the injection.
Compound
Spray and drops are a solution of the main active ingredient (xylometazoline hydrochloride). Each milligram of nasal remedy for children contains 500 mg of this substance.
Xylometazoline hydrochloride is a topical alpha-adrenergic agonist that has a vasoconstrictor effect on the nasal mucosa. A runny nose should be treated as early as possible. This is where Rhinonorm nasal remedies come to the rescue. The blood vessels narrow, the swelling subsides, and the child can breathe freely again.
Rinonorm preparations include stabilizers, including citric acid and glycerol, as auxiliary components. The basis of the solution is distilled water.
Operating principle
If you get a viral or bacterial infection on the mucous membrane, the pathogenic organism invades its cells. First, dryness and burning appear in the nose, and then swelling of the mucous membrane occurs. Simultaneously with the swelling, active discharge begins and nasal congestion appears.
Some parents believe that colds are not caused by an infection and therefore do not need to be treated. Hypothermia itself, which, as a rule, leads to a cold, is indeed not a disease. But the disease we call a cold occurs when a child's immune system weakens due to hypothermia. At this point, children are more vulnerable to bacterial infections.
A runny nose is not a completely harmless disease. Difficulty breathing leads to decreased oxygen concentration in the blood. Internal organs and the child’s tissues begin to lack it. This condition is called hypoxia. Prolonged hypoxia negatively affects the health of children.
When using "Rinonorm", the alpha-adrenergic agonist, when it gets on the mucous membrane, promotes the narrowing of arterioles (small arteries in the nose). The flow of blood to the mucous membrane is reduced, the swelling subsides, and the redness also becomes less pronounced. When breathing is restored, children begin to feel better, and the lethargy and drowsiness that accompanies difficulty breathing disappear.
The effect of nasal preparations "Rinonorm" lasts up to 6-8 hours. Therefore, if you give them to your child before bedtime, he is guaranteed to sleep peacefully throughout the night.
In addition, timely treatment will help avoid various complications in which inflammation can spread to the mucous membrane of the pharynx and larynx. This can cause diseases such as sinusitis, laryngitis, pharyngitis, and otitis media.
If the appearance of a runny nose is associated with a seasonal exacerbation of allergies or contact with an allergen, then the action of “Rinonorm” will also alleviate this condition. In this case, the product should be used in combination with anti-allergenic drugs.
Indications
Rhinonrom nasal remedies can be taken if a child has a runny nose, regardless of its cause: viral, bacterial infection or allergy. "Rinonorm" is indicated for acute sinusitis, that is, inflammation of the paranasal cavities, as well as for exacerbation of the chronic stage of this disease.
If a child develops a runny nose, you can use children’s “Rinonorm” even before consulting a doctor, since it is important to “catch” the disease at the very beginning and prevent it from developing. But it is imperative to consult a doctor if your child is sick. Parents can write down the names of all the medications they gave the child, and the doctor, based on the child's symptoms and individual health indicators, can adjust the treatment method.
"Rinonorm" is also successfully used as part of complex therapy in the treatment of otitis media. The drug relieves swelling and alleviates the child’s condition. But you should not immediately use “Rinonorm” if a child has an earache. It is better to first consult a doctor who will prescribe the appropriate treatment.
“Rinonorm” is also indicated in preparing children for various manipulations, procedures and surgical operations in the nose.
At what age is it prescribed?
Even in pediatric dosage, doctors do not recommend giving Rinonorm to a child under 2 years of age. This is due to the characteristics of young children, who have many physiological processes in the body proceed differently than in adults and older children. Babies under the age of one year are especially vulnerable in this sense.
The appearance of a runny nose small child who cannot breathe through his mouth is very dangerous. Parents should immediately consult a doctor who will recommend an approved drug. Pharmacists in pharmacies are also qualified to advise the medicine that is suitable for your baby.
Contraindications
Strict contraindications to the use of Rinonorm drugs are increased individual sensitivity to the components. It is also not recommended to use an alpha-adrenergic agonist if there is damage to the mucous membrane in the child’s nose: wounds, scratches, crusts.
Alpha-adrenergic agonists are not used simultaneously with inhibitors and tricyclic antidepressants.
The use of nasal preparations "Rinonorm", intended for adults, is contraindicated for children under 10 years of age. In the absence of a medicine with a child dosage, many parents decide to give their child an adult “Rinonorm”. But doctors believe that this is not necessary. Using a drug with a higher concentration of the active ingredient may lead to overdose symptoms and worsening the child’s condition.
Only under the constant supervision of a doctor is Rinonorm given to children suffering from diabetes and severe heart disease.
Side effects
In some cases, after using Rinon nasal medications, a local reaction may occur in the form of a feeling of dryness or burning in the nose, and sometimes in the mucous membrane of the mouth and larynx. Children may complain of headaches bad dream, sometimes parents note increased excitability and poor health of the child, and sometimes an increase in blood pressure may be observed. In the most severe cases, nausea and skin rashes may occur.
If one of these symptoms is noticed, even if there is a possibility that its appearance is not associated with Rinonorm, you should stop treatment with the drug and consult a doctor. If treatment is continued, the symptoms may worsen and the child’s condition may worsen.
Instructions for use
Before intranasal administration of the drug, it is necessary to clear the child’s nose of accumulated mucus.
When using the spray for a child aged 2 to 10 years, it is recommended to do one spray up to 3 times a day. One injection corresponds to 0.14 ml of solution. In this case, at least 6 hours must pass between two doses.
Used for children over 10 years of age adult form spray with a concentration of 0.1%. Also, one spray into each nasal passage no more than 3 times a day is sufficient. The total duration of treatment is no more than 7 days.
The use of "Rinonorm" drops for children from 0 to 6 years is allowed 1-2 times a day, 1-2 drops. For this age category use drops "Rinonorm" 0.05%. Children over 6 years old are given Rhinonorm drops 0.1%, 2-3 drops up to 4 times a day.
Rhinonorm nasal gel can only be given to children over 7 years of age. The gel is placed in the nose up to 4 times a day, including before bedtime.
Overdose
When treated with Rinonorm drugs, overdose is observed in rare cases. Symptoms include increased blood pressure and arrhythmia. With a large overdose, loss of consciousness is possible.
If a child accidentally takes a large amount of the drug orally, you should urgently call ambulance» . If for some reason it is impossible to call specialists, you should do gastric lavage yourself. This is not the most pleasant procedure. The child should be given from 150 ml (for newborns) to 600 ml of water (for children over 7 years old). Then you need to induce vomiting in the child.
It is important to note that gastric lavage is effective only for one to two hours after taking the medicine.
In any case, after washing, or if it was not possible to do it, you need to give the child activated carbon or any sorbent, as well as a laxative. This will help remove unwanted substances from the body as quickly as possible.
Doctors advise taking an alpha-agonist overdose seriously, since it is a strong vasoconstrictor.
Interaction with other drugs
It is known that simultaneous use with MAO inhibitors leads to an increase in blood pressure, and when combining treatment with Rinonorm with tri- or tetracyclic antidepressants, the effect of the drug increases, which can cause overdose symptoms.
Terms of sale and storage
Rinonorm drugs are classified as over-the-counter drugs. After purchasing from a pharmacy, the bottle or canister should be stored at an air temperature of no higher than 25 C. If the container is kept closed, the shelf life is 3 years from the date of issue. After opening, the medicine can be used for one year. The production date is always indicated on the packaging.
Rinonorm Teva is a nasal spray with a vasoconstrictor effect, an alpha-adrenergic agonist for topical use in ENT practice. Causes a narrowing of arterioles, leading to a decrease in hyperemia and swelling of the mucous membranes of the nasopharynx and a decrease in secretion.
Active ingredient: Xylometazoline. Dosage form– nasal spray 0.1% and 0.05% (15 mg each in dark glass bottles equipped with a dispenser, 1 bottle in a cardboard box).
The use of Rinonorm Teva causes a narrowing of the arterioles, leading to a decrease in hyperemia and swelling of the mucous membranes of the nasopharynx and a decrease in secretion.
A distinct local effect of the spray is detected within a few minutes and persists for several hours (up to 6-8 hours), manifesting itself in the restoration of patency of the nasal passages, sinus openings and Eustachian tubes.
When used as directed (in the nose), the active substance is practically not absorbed, the concentrations in the blood plasma are very small (not analytically determined).
Composition of 10 ml spray:
- xylometazoline hydrochloride – 10 mg or 5 mg;
- auxiliary components: water for injection, sodium citrate dihydrate, citric acid monohydrate, glycerol 85%.
Indications for use
What does Rinonorm Teva help with? According to the instructions, the spray is prescribed in the following cases:
- Purulent and unspecified otitis media;
- Acute nasopharyngitis (runny nose);
- Acute sinusitis;
- Acute viral or bacterial rhinitis;
- Allergic rhinitis caused by pollen;
- Acute otitis media (to reduce swelling of the mucous membrane of the Eustachian tube);
- Chronic sinusitis;
- Preparatory procedures for diagnostic procedures in the nasal passages.
Instructions for use of Rinonorm Teva, spray dosage
- Adults and children over 10 years old - apply 0.1% spray
- Children aged 2 to 10 years – spray for children 0.05%
The maximum dosage is 1 dose every 6 hours. The amount of liquid entering the nasal passage (1 dose) = 0.14 ml of solution.
The duration of treatment should not exceed 7 days. With prolonged use it is addictive!
Side effects
The instruction warns about the possibility of developing the following side effects when prescribing Rinonorm Teva spray:
- Local reactions: burning sensation and dryness of the nasal mucosa; rarely - irritation of the mucous membrane of the nose, mouth and larynx.
- From the side of the central nervous system: rarely – headache; rarely (< 1/10 000) – бессонница, повышенная возбудимость.
- From the cardiovascular system: extremely rare (< 1/10 000) – аритмия, увеличение АД.
- Other: rarely – nausea; rarely (< 1/10 000) – кожные реакции.
Contraindications
It is contraindicated to prescribe Rinonorm Teva in the following cases:
- Atrophic (dry) rhinitis;
- Angle-closure glaucoma;
- Condition after hypophysectomy;
- Simultaneous use of MAO inhibitors and tricyclic antidepressants;
- Children under 2 years of age (spray for children);
- Children under 10 years of age (spray for adults);
- Hypersensitivity to xylometazoline or other components of the drug.
Carefully
- For arterial hypertension,
- Severe heart disease,
- Hyperthyroidism,
- Diabetes mellitus
- Patients taking bromocriptine.
Overdose
In rare cases of overdose, which occurs mainly in children, arrhythmia, increased blood pressure, and in some cases loss of consciousness may occur.
Treatment is symptomatic. In serious cases, non-selective alpha-blockers can be used to lower blood pressure, as well as intubation and mechanical ventilation. Vasoconstrictor drugs are contraindicated.
If you accidentally ingest a moderate or large amount of the spray, you should take activated charcoal and a laxative (for example, sodium sulfate), and do a gastric lavage.
Vasoconstrictor drug for topical use in ENT practice
Active substance
Release form, composition and packaging
◊ Dosed nasal spray (for children) 0.05%
◊ Nasal spray dosed 0.1% in the form of a clear, colorless solution.
Excipients: citric acid monohydrate, sodium citrate dihydrate, glycerol 85%, water for injection.
15 ml - dark glass bottles (1) with a dispensing device and a nosepiece - cardboard packs.
pharmachologic effect
Alpha adrenergic agonist for local use in ENT practice.
When applied topically, xylometazoline causes constriction of arterioles, leading to a decrease in hyperemia and swelling of the mucous membranes of the nasopharynx and a decrease in secretion. A distinct local effect of the drug is detected within a few minutes and persists for several hours (up to 6-8 hours), manifesting itself in the restoration of patency of the nasal passages, sinus openings and Eustachian tubes. Restoring air patency of the nasopharynx improves the patient’s well-being and reduces the risk of possible complications caused by stagnation of mucous secretions.
Pharmacokinetics
When applied topically, xylometazoline is practically not absorbed, so the concentrations in the blood are very small (not analytically determined).
Indications
Rinonorm is used as symptomatic therapy for the following diseases and conditions:
- acute viral or bacterial rhinitis;
- acute allergic rhinitis;
- acute sinusitis or exacerbation of chronic sinusitis;
- acute otitis media (to reduce swelling of the mucous membrane of the Eustachian tube);
— preparing the patient for diagnostic procedures in the nasal passages.
Contraindications
- atrophic (dry) rhinitis;
- angle-closure glaucoma;
— condition after hypophysectomy;
- simultaneous use of MAO inhibitors and tricyclic antidepressants;
— childhood up to 2 years (for spray for children);
- children under 10 years of age (for adult spray);
- hypersensitivity to xylometazoline or other components of the drug.
WITH caution the drug should be used for arterial hypertension, severe heart disease, hyperthyroidism, diabetes mellitus and patients taking.
Dosage
Adults and children over 10 years old Prescribe Rinonorm nasal spray 0.1%, 1 dose (1 press on the piston device) in each nasal passage no more than 3 times a day.
Children aged 2 to 10 years Prescribe Rinonorm nasal spray for children 0.05%, 1 dose (1 press on the piston device) in each nasal passage no more than 3 times a day.
The maximum possible use of the drug is no more than 7 times a day. The interval between drug administration should not be less than 6 hours.
The amount of liquid entering the patient’s nasal passage (1 dose) is 0.14 ml of solution.
To avoid complications in the form of resumption of symptoms of the disease, the duration of continuous use of the drug should not exceed 7 days.
Before using the drug, you should clear the nasal passages of secretions. During administration of the drug, you should take a light breath through the nose.
Side effects
Local reactions: burning sensation and dryness of the nasal mucosa; rarely - irritation of the mucous membrane of the nose, mouth and larynx.
Treatment: symptomatic therapy under supervision is indicated. In serious cases, non-selective alpha-blockers can be used to lower blood pressure, as well as intubation and mechanical ventilation. Vasoconstrictor drugs are contraindicated. If you accidentally take a moderate or large amount of the drug orally, you should also take a laxative (for example, sodium sulfate) and perform a gastric lavage.
Drug interactions
Concomitant use of tri- or tetracyclic antidepressants may increase the systemic exposure of xylometazoline.
When taking the drug simultaneously with MAO inhibitors, there may be a risk of increased blood pressure.